Synthesis and Preclinical Evaluation of 2-(4-[<sup>18</sup>F]Fluorophenyl)imidazo[1,2-h][1,7]naphthyridine ([<sup>18</sup>F]FPND-4): An Aza-Fused Tricyclic Derivative as Positron Emission Tomography Tracer for Neurofibrillary Tangle Imaging-Reference-Cited by-同舟云学术

Synthesis and Preclinical Evaluation of 2-(4-[¹⁸F]Fluorophenyl)imidazo[1,2-h][1,7]naphthyridine ([¹⁸F]FPND-4): An Aza-Fused Tricyclic Derivative as Positron Emission Tomography Tracer for Neurofibrillary Tangle Imaging

Published:2023-05-18 Issue:14 Volume:66 Page:9561-9576
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Tianqing¹,Li Yuying¹,Zhang Xiaojun²,Yao An¹,Wang Yan³,Yao Shulin²,Chen Baian⁴⁵,Yan Xiao-xin³,Dai Jiapei⁶,Zhang Jinming²,Cui Mengchao¹⁷^ORCID

Affiliation:

1. Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China

2. Department of Nuclear Medicine, Chinese PLA General Hospital, Beijing 100853, China

3. Department of Anatomy and Neurobiology, Central South University Xiangya School of Medicine, Changsha 410013, China

4. School of Basic Medical Sciences, Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing, 100069, China

5. Department of Laboratory Animal Sciences, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China

6. Wuhan Institute for Neuroscience and Neuroengineering, South-Central Minzu University, Wuhan 430074, China

7. Center for Advanced Materials Research, Beijing Normal University at Zhuhai, Zhuhai 519087, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00239

Reference43 articles.

1. New insights into atypical Alzheimer's disease in the era of biomarkers

2. A Brief History of Tau

3. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

4. Cryo-EM structures of tau filaments from Alzheimer’s disease

5. Structures of filaments from Pick’s disease reveal a novel tau protein fold

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery and Evaluation of Imidazo[2,1-b][1,3,4]thiadiazole Derivatives as New Candidates for α-Synuclein PET Imaging;Journal of Medicinal Chemistry;2024-07-31

2. Diversification of Bipyridines and Azaheterocycles via Nucleophilic Displacement of Trimethylammoniums;ACS Organic & Inorganic Au;2024-07-17

3. Current status of PET tracers for the early diagnosis of Alzheimer's disease;TrAC Trends in Analytical Chemistry;2024-03

4. Diagnostic and Therapeutic Radiopharmaceuticals: A “Hot” Topic;Journal of Medicinal Chemistry;2023-12-18

5. Diagnostic and Therapeutic Radiopharmaceuticals: A “Hot” Topic;ACS Pharmacology & Translational Science;2023-12-18