Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs-Reference-Cited by-同舟云学术

Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs

Published:2024-03-13 Issue:6 Volume:67 Page:4641-4654
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shah Rishi R.¹²^ORCID,De Vita Elena²³^ORCID,Sathyamurthi Preethi S.¹,Conole Daniel²^ORCID,Zhang Xinyue²,Fellows Elliot¹,Dickinson Eleanor R.¹^ORCID,Fleites Carlos M.¹,Queisser Markus A.¹^ORCID,Harling John D.¹^ORCID,Tate Edward W.²⁴^ORCID

Affiliation:

1. GSK, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, U.K.

2. Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.

3. Department of Biochemistry, School of Biological and Behavioural Sciences, Queen Mary University of London, 327 Mile End Road, London E1 4NS, U.K.

4. The Francis Crick Institute, 1 Midland Road, London NW1 1AT, U.K.

Funder

Engineering and Physical Sciences Research Council

Imperial College London

HORIZON EUROPE Marie Sklodowska-Curie Actions

China Scholarship Council

Publisher

American Chemical Society (ACS)