Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader-Reference-Cited by-同舟云学术

Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader

Published:2023-11-15 Issue:22 Volume:66 Page:15269-15287
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hu Linghao¹^ORCID,Li Huiyun¹²,Qin Junlin³,Yang Dan¹⁴,Liu Jieming¹,Luo Xiaomin¹,Ma Jingkun,Luo Cheng¹³^ORCID,Ye Fei⁵^ORCID,Zhou Yubo¹,Li Jia¹²³,Wang Mingliang¹⁴

Affiliation:

1. Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan Tsuihang New District, Guangdong 528400, China

2. School of Pharmacy, Zunyi Medical University, Zunyi 563000, Guizhou China

3. School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China

4. School of Pharmaceutical Sciences, Southern Medical University, No.1023, South Shatai Road, Baiyun District, Guangzhou 510515, Guangdong, China

5. College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China

Funder

Guangdong Provincial Department of Science and Technology

China Postdoctoral Science Foundation

Shanghai Science and Technology Development Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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