Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases
Author:
Affiliation:
1. Department of Medicinal Chemistry and Molecular Pharmacology, Department of Chemistry, Center for Cancer Research, and Institute for Drug Discovery, Purdue University, 720 Clinic Drive, West Lafayette, Indiana 47907, United States
Funder
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
General Medicine,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.6b00537
Reference52 articles.
1. Tyrosine phosphorylation: thirty years and counting
2. Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction
3. Kinase Drug Discovery – What’s Next in the Field?
4. Protein tyrosine phosphatases as potential therapeutic targets
5. Small-molecule kinase inhibitors: an analysis of FDA-approved drugs
Cited by 141 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. In silico identification of putative druggable pockets in PRL3, a significant oncology target;Biochemistry and Biophysics Reports;2024-09
2. Mapping spatial organization and genetic cell-state regulators to target immune evasion in ovarian cancer;Nature Immunology;2024-08-23
3. Mapping protein conformational landscapes from crystallographic drug fragment screens;2024-07-30
4. From Tyrosine Kinases to Tyrosine Phosphatases: New Therapeutic Targets in Cancers and Beyond;Pharmaceutics;2024-07-01
5. Targeting the undruggables—the power of protein degraders;Science Bulletin;2024-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3