Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer’s Disease: In Vivo Studies on Mouse Models-Reference-Cited by-同舟云学术

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Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer’s Disease: In Vivo Studies on Mouse Models

Published:2023-04-24 Issue:9 Volume:66 Page:6372-6390
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jun Joonhong¹,Moon Hyungwoo¹,Yang Songyi¹,Lee Junghun¹,Baek Jihyun¹,Kim Hyejin¹,Cho Hyunwook¹,Hwang Kyungrim²,Ahn Soyeon²,Kim Yuro²,Kim Gibeom²,Kim HyunTae²,Kwon Hoseok²,Hah Jung-Mi¹^ORCID

Affiliation:

1. Department of Pharmacy & Institute of Pharmaceutical Science and Technology, College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do 15588, Republic of Korea

2. Research Center, Samjin Pharm. Co. Ltd. 90, Magokjungang 10-ro, Gangseo-gu, Seoul 07794, Republic of Korea

Funder

National Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00393

Reference54 articles.

1. Classification and basic pathology of Alzheimer disease

2. Alzheimer's Disease: The Amyloid Cascade Hypothesis

3. Molecular mechanisms of neurodegeneration in Alzheimer's disease

4. Structure and Pathology of Tau Protein in Alzheimer Disease

5. The JNK/c-Jun cascade and Alzheimer's disease

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1. Update on JNK inhibitor patents: 2015 to present;Expert Opinion on Therapeutic Patents;2024-09-08

2. Recent Molecular Targets and Their Ligands for the Treatment of Alzheimer Disease;Current Topics in Medicinal Chemistry;2024-08-20

3. Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases;ACS Chemical Neuroscience;2024-04-22

4. Physiological JNK3 Concentrations Are Higher in Motor-related and Disease-implicated Brain Regions of C57BL6/J Mice;2024-01-20

5. Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives;European Journal of Medicinal Chemistry;2023-12

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