Macrocycles in Drug Discovery─Learning from the Past for the Future
Author:
Affiliation:
1. Department of Chemistry-BMC, Uppsala University, Box 576, SE-751 23 Uppsala, Sweden
2. Department of Molecular Biotechnology and Health Sciences, University of Torino, Quarello 15, 10135 Torino, Italy
Funder
Vetenskapsr?det
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00134
Reference82 articles.
1. New Chemical Modalities and Strategic Thinking in Early Drug Discovery
2. New Modalities for Challenging Targets in Drug Discovery
3. Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
4. Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
5. Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs
Cited by 69 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Macrocyclic-based strategy in drug design: From lab to the clinic;European Journal of Medicinal Chemistry;2024-11
2. Molecular properties, including chameleonicity, as essential tools for designing the next generation of oral beyond rule of five drugs;ADMET and DMPK;2024-08-27
3. The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery;Journal of Medicinal Chemistry;2024-08-22
4. The Influence of Disulfide, Thioacetal and Lanthionine‐Bridges on the Conformation of a Macrocyclic Peptide;Chemistry – A European Journal;2024-08-20
5. Targeting Solvent-Front Mutations for Kinase Drug Discovery: From Structural Basis to Design Strategies;Journal of Medicinal Chemistry;2024-08-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3