Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen-Reference-Cited by-同舟云学术

Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen

Published:2023-05-02 Issue:10 Volume:66 Page:6938-6958
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Pan¹²³⁴,Zhou Ying¹⁴,Li Xiaobo¹⁴,Yang Jun¹⁴,Zheng Zhiwei¹³⁴,Zou Yu¹⁴,Li Xiang¹⁴,Liao Jing¹⁴,Dai Jintian⁴,Xu Yuye⁴,Yin Lina²,Chen Gaozhi¹,Gu Jing⁵,Ouyang Qin⁵^ORCID,Cho Won-Jea³,Tang Qidong¹⁴,Liang Guang¹²⁴^ORCID

Affiliation:

1. Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China

2. School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou 310053, China

3. College of Pharmacy, Chonnam National University, Gwangju 61186, Korea

4. Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China

5. Department of Medicinal Chemistry, College of Pharmacy, Third Military Medical University, Chongqing 400038, China

Funder

Wenzhou Medical University

University of Chinese Academy of Sciences

Third Military Medical University

National Natural Science Foundation of China

Zhejiang Province