Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2-Reference-Cited by-同舟云学术

Design, Synthesis, and Antitumor Efficacy of Substituted 2-Amino[1,2,4]triazolopyrimidines and Related Heterocycles as Dual Inhibitors for Microtubule Polymerization and Janus Kinase 2

Published:2023-10-19 Issue:21 Volume:66 Page:15006-15024
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Li¹,Hu Yunfei¹,Lu Zhonghui¹,Lin Zeyin¹,Li Lanqing¹,Wu Jia-Qiang¹^ORCID,Yu Zhi-Ling²^ORCID,Wang Chunye³,Chen Wen-Hua¹^ORCID,Hu Jinhui¹^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, P. R. China

2. Center for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong 852, P. R. China

3. Department of Pharmacy, Huizhou First Maternal and Child Health Care Hospital, Huizhou 516000, P. R. China

Funder

Science and Technology Planning Project of Guangdong Province

National College Students Innovation and Entrepreneurship Training Program

Department of Education of Guangdong Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01690