Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors-Reference-Cited by-同舟云学术

Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors

Published:2023-06-30 Issue:13 Volume:66 Page:8808-8821
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kesteleyn Bart¹^ORCID,Bardiot Dorothée²,Bonfanti Jean-François³,De Boeck Benoît¹,Goethals Olivia⁴,Kaptein Suzanne J. F.⁵,Stoops Bart¹,Coesemans Erwin¹,Fortin Jérôme³,Muller Philippe³,Doublet Frédéric³,Carlens Gunter²,Koukni Mohamed²,Smets Wim²,Raboisson Pierre¹,Chaltin Patrick²⁶,Simmen Kenny¹,Van Loock Marnix⁴,Neyts Johan⁵⁷,Marchand Arnaud²^ORCID,Jonckers Tim H. M.¹^ORCID

Affiliation:

1. Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium

2. CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium

3. Janssen Infectious Diseases Discovery, Janssen-Cilag, Chaussée du Vexin, 27106 Val de Reuil, France

4. Janssen Global Public Health R&D, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium

5. Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Herestraat 49, 3000 Leuven, Belgium

6. Centre for Drug Design and Discovery (CD3), KU Leuven, Bioincubator 2, Gaston Geenslaan 2, Leuven 3000, Belgium

7. Global Virus Network (GVN), Baltimore, Maryland 21201, United States

Funder

Wellcome Trust

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00403

Reference30 articles.

1. Epidemiology of dengue: past, present and future prospects

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3. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013

4. The current and future global distribution and population at risk of dengue

5. Pathogenesis of Dengue: Dawn of a New Era

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