Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2-Reference-Cited by-同舟云学术

Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2

Published:2023-07-31 Issue:18 Volume:66 Page:12911-12930
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Casella Bianca Maria¹^ORCID,Farmer James P.²^ORCID,Nesheva Desislava N.²,Williams Huw E. L.³,Charlton Steven J.²⁴^ORCID,Holliday Nicholas D.²⁵^ORCID,Laughton Charles A.¹^ORCID,Mistry Shailesh N.¹^ORCID

Affiliation:

1. Division of Biomolecular Sciences and Medicinal Chemistry, School of Pharmacy, University of Nottingham Biodiscovery Institute, Nottingham NG7 2RD, UK

2. Division of Physiology, Pharmacology & Neuroscience, Medical School, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK

3. School of Chemistry, University of Nottingham Biodiscovery Institute, Nottingham NG7 2RD, UK

4. OMass Therapeutics Ltd., Oxford OX4 2GX, UK

5. Excellerate Bioscience Ltd., Biocity, University of Nottingham, Nottingham NG1 1GF, UK

Funder

University of Nottingham

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00849