Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε-Reference-Cited by-同舟云学术

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε

Published:2018-04-09 Issue:9 Volume:61 Page:4087-4102
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

García-Reyes Balbina¹,Witt Lydia²,Jansen Björn²,Karasu Ebru¹,Gehring Tanja¹,Leban Johann³,Henne-Bruns Doris¹,Pichlo Christian⁴,Brunstein Elena⁴,Baumann Ulrich⁴,Wesseler Fabian⁵,Rathmer Bernd⁵,Schade Dennis⁵⁶,Peifer Christian²^ORCID,Knippschild Uwe¹

Affiliation:

1. Department of General and Visceral Surgery, Ulm University Hospital, Albert-Einstein-Allee 23, D-89081 Ulm, Germany

2. Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, D-24116 Kiel, Germany

3. Oncotyrol GmbH, Karl-Kapferer-Straße 5, 6020 Innsbruck, Austria

4. Department for Chemistry, University of Cologne, Zülpicher Str. 47B, D-50674 Cologne, Germany

5. Department of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Str. 6, D-44227 Dortmund, Germany

6. Institute of Pharmacy, Ernst-Moritz-Arndt-University of Greifswald, Felix-Hausdorff-Str. 1, D-17489 Greifswald, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Deutscher Akademischer Austauschdienst

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00095

Reference63 articles.

1. The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis

2. Cytoskeletal dynamics and cell signaling during planar polarity establishment in theDrosophilaembryonic denticle

3. Casein kinase 1: Complexity in the family

4. Identification of four alternatively spliced isoforms of chicken casein kinase I alpha that are all expressed in diverse cell types

5. Four Casein Kinase I Isoforms Are Differentially Partitioned between Nucleus and Cytoplasm

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