De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors-Reference-Cited by-同舟云学术

De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors

Published:2018-07-03 Issue:17 Volume:61 Page:7486-7502
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Ying¹^ORCID,Zhao Hongyu¹,Brewer Jason T.¹,Li Huanqiu¹,Lao Yanbin¹,Amberg Willi²^ORCID,Behl Berthold²,Akritopoulou-Zanze Irini¹,Dietrich Justin¹,Lange Udo E. W.²,Pohlki Frauke²,Hoft Carolin²,Hornberger Wilfried²,Djuric Stevan W.¹,Sydor Jens²,Mezler Mario²,Relo Ana Lucia²,Vasudevan Anil¹^ORCID

Affiliation:

1. AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

2. Neuroscience Research, AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061 Ludwigshafen, Germany

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00295

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