Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors-Reference-Cited by-同舟云学术

Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors

Published:2022-03-22 Issue:1 Volume:37 Page:952-972
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Yu Jiang¹²,Gou Wenfeng¹,Shang Haihua¹^ORCID,Cui Yating¹,Sun Xiao¹,Luo Lingling¹,Hou Wenbin¹,Sun Tiemin²,Li Yiliang¹

Affiliation:

1. Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China

2. Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, China

Funder

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences

Fundamental Research Funds for the Central Universities

Science and Technology Project of Tianjin

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2053524

Reference47 articles.

1. The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

2. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

3. Cancer Susceptibility and the Functions of BRCA1 and BRCA2

4. Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells

5. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Poly (ADP-ribose) polymerase (PARP) inhibitors as anticancer agents: An outlook on clinical progress, synthetic strategies, biological activity, and structure-activity relationship;European Journal of Medicinal Chemistry;2024-08

2. A Novel Inhibitor of Poly(ADP-Ribose) Polymerase-1 Inhibits Proliferation of a BRCA-Deficient Breast Cancer Cell Line via the DNA Damage–Activated cGAS–STING Pathway;Chemical Research in Toxicology;2024-03-27

3. An Update on Poly(ADP-ribose) Polymerase I-A Brief Review;Mini-Reviews in Medicinal Chemistry;2023-10

4. Recent advances in structural types and medicinal chemistry of PARP-1 inhibitors;Medicinal Chemistry Research;2022-06-10