Recent advances in structural types and medicinal chemistry of PARP-1 inhibitors-Reference-Cited by-同舟云学术

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Recent advances in structural types and medicinal chemistry of PARP-1 inhibitors

Published:2022-06-10 Issue:8 Volume:31 Page:1265-1276
ISSN:1054-2523
Container-title:Medicinal Chemistry Research
language:en
Short-container-title:Med Chem Res

Author:

Yu Ling,Yan Zhi-wei,Wang You-de,Miao Hao,Zhao Jing-yi,Pang Chong,Li Shuai

Funder

Science and Technology Project of Hebei Education Department

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Link

https://link.springer.com/content/pdf/10.1007/s00044-022-02919-6.pdf

Reference78 articles.

1. Guo C, Wang L, Li X, Wang S, Yu X, Xu K, et al. Discovery of novel bromophenol-thiosemicarbazone hybrids as potent selective inhibitors of Poly(ADP-Ribose) polymerase-1 (PARP-1) for use in cancer. J Med Chem. 2019;62:3051–67.

2. Ekhteiari Salmas R, Unlu A, Bektaş M, Yurtsever M, Mestanoglu M, Durdagi S. Virtual screening of small molecules databases for discovery of novel PARP-1 inhibitors: combination of in silico and in vitro studies. J Biomol Struct Dyn. 2017;35:1899–915.

3. Zhao Y, Zhang L, Jiang T, Long J, Ma Z, Lu A, et al. The ups and downs of Poly (ADP-ribose) Polymerase-1 inhibitors in cancer therapy – current progress and future direction. Eur J Med Chem. 2020;203:112570.

4. Jain PG, Patel BD. Medicinal chemistry approaches of poly ADP-Ribose polymerase 1 (PARP1) inhibitors as anticancer agents – a recent update. Eur J Med Chem. 2019;165:198–215.

5. Chen X, Huan X, Liu Q, Wang Y, He Q, Tan C, et al. Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-Yl)-benzoimidazole carboxamides as novel orally efficacious poly(ADP-Ribose)polymerase (PARP) inhibitors. Eur J Med Chem. 2018;145:389–403.

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4. Design, synthesis and biological evaluation of matrine contains benzimidazole derivatives as dual TOPOI and PARP inhibitors for cancer therapy;European Journal of Medicinal Chemistry;2024-04

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