Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure–Activity Analysis-Reference-Cited by-同舟云学术

Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure–Activity Analysis

Published:2019-01-09 Issue:3 Volume:62 Page:1443-1454
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gu Chunfang¹,Stashko Michael A.²,Puhl-Rubio Ana C.²,Chakraborty Molee³,Chakraborty Anutosh³,Frye Stephen V.²^ORCID,Pearce Kenneth H.²,Wang Xiaodong²^ORCID,Shears Stephen B.¹^ORCID,Wang Huanchen¹

Affiliation:

1. Inositol Signaling Group, Signal Transduction Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, United States

2. Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. Department of Pharmacology and Physiology, Saint Louis University School of Medicine, M370, Schwitalla Hall, 1402 South Grand Boulevard, Saint Louis, Missouri 63104, United States

Funder

National Institute of Environmental Health Sciences

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01593

Reference58 articles.

1. Back in the water: the return of the inositol phosphates

2. The Expanding Significance of Inositol Polyphosphate Multikinase as a Signaling Hub