Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases-Reference-Cited by-同舟云学术

Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases

Published:2018-10-15 Issue:21 Volume:61 Page:9551-9567
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Erra Montse^ORCID,Taltavull Joan^ORCID,Bernal Francisco Javier,Caturla Juan Francisco,Carrascal Marta,Pagès Lluís^ORCID,Mir Marta,Espinosa Sònia,Gràcia Jordi^ORCID,Domínguez María,Sabaté Mar,Paris Stéphane,Maldonado Mónica,Hernández Begoña,Bravo Mónica,Calama Elena,Miralpeix Montserrat,Lehner Martin D.,Calbet Marta

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00873

Reference11 articles.

1. PI3K signalling: the path to discovery and understanding

2. Targeting phosphoinositide 3-kinase δ for allergic asthma

3. Targeting phosphoinositide 3-kinase δ for the treatment of respiratory diseases

4. Optimisation of DMPK by the Inhaled Route: Challenges and Approaches

5. RV1729 and RV6153 (RespiVert) and GSK2269557 (GSK) at clinicaltrials.gov.

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. From lab to clinic: The discovery and optimization journey of PI3K inhibitors;European Journal of Medicinal Chemistry;2024-11

2. Discovery and Optimization of Pyridazinones as PI3Kδ Selective Inhibitors for Administration by Inhalation;Journal of Medicinal Chemistry;2024-06-22

3. Optimization of virtual screening against phosphoinositide 3-kinase delta: Integration of common feature pharmacophore and multicomplex-based molecular docking;Computational Biology and Chemistry;2024-04

4. Designing inhaled small molecule drugs for severe respiratory diseases: an overview of the challenges and opportunities;Expert Opinion on Drug Discovery;2024-02-26

5. Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and apoptotic inducers;Journal of Enzyme Inhibition and Medicinal Chemistry;2024-02-13