Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor Agents-Reference-Cited by-同舟云学术

Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor Agents

Published:2018-07-25 Issue:16 Volume:61 Page:7245-7260
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

He Shipeng¹,Dong Guoqiang²,Wu Shanchao²,Fang Kun¹,Miao Zhenyuan²^ORCID,Wang Wei¹³^ORCID,Sheng Chunquan²^ORCID

Affiliation:

1. School of Pharmacy, East China University of Science and Technology, Shanghai 200237, P.R. China

2. Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, P.R. China

3. Department of Chemistry and Chemical Biology, University of New Mexico, MSC03 2060, Albuquerque, New Mexico 87131-0001, United States

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00664

Reference62 articles.

1. p53, guardian of the genome

2. Surfing the p53 network

3. p53 and Human Cancer: The First Ten Thousand Mutations

4. p53 in health and disease

5. MDM2 — master regulator of the p53 tumor suppressor protein

Cited by 55 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of Novel p53-MDM2 Inhibitor (RG7388)-Conjugated Platinum^IV Complexes as Potent Antitumor Agents;Journal of Medicinal Chemistry;2024-05-22

2. Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment;European Journal of Pharmaceutical Sciences;2024-01

3. Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein–Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy;Journal of Medicinal Chemistry;2023-12-07

4. N-(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity;Journal of Medicinal Chemistry;2023-10-05

5. Discovery of Pyrazolone Carbothioamide Derivatives as Inhibitors of the Pdr1-KIX Interaction for Combinational Treatment of Azole-Resistant Candidiasis;Journal of Medicinal Chemistry;2023-08-16