A Cinchona Alkaloid Antibiotic That Appears To Target ATP Synthase in Streptococcus pneumoniae
Author:
Affiliation:
1. Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing 100084, People’s Republic of China
2. Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States
Funder
Peking Union Medical College Hospital
State Key Laboratory of Bioactive Substance and Function of Natural Medicines
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01353
Reference74 articles.
1. Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2013 https://www.cdc.gov/drugresistance/threat-report-2013/ (accessed Aug 20, 2018).
2. http://www.who.int/mediacentre/factsheets/fs331/en/ (accessed Aug 20, 2018).
3. Emergence of Multidrug-Resistant Pneumococcal Serotype 35B among Children in the United States
4. Multidrug Resistance in Non-PCV13 Serotypes ofStreptococcus pneumoniaein Northern Japan, 2014
5. Changes in Pneumococcal Serotypes and Antimicrobial Resistance after Introduction of the 13-Valent Conjugate Vaccine in the United States
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