Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach-Reference-Cited by-同舟云学术

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

Published:2018-06-08 Issue:13 Volume:61 Page:5719-5732
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hoffer Laurent¹,Voitovich Yuliia V.¹²,Raux Brigitt¹,Carrasco Kendall¹,Muller Christophe³,Fedorov Aleksey Y.²,Derviaux Carine³,Amouric Agnès¹³,Betzi Stéphane¹,Horvath Dragos⁴^ORCID,Varnek Alexandre⁴^ORCID,Collette Yves¹³,Combes Sébastien¹,Roche Philippe¹^ORCID,Morelli Xavier¹³^ORCID

Affiliation:

1. CRCM, CNRS, Inserm, Institut Paoli-Calmettes, Aix-Marseille University, 13009 Marseille, France

2. Department of Organic Chemistry, Lobachevsky State University of Nizhni Novgorod, 23 Gagarin Avenue, 603950 Nizhni Novgorod, Russia

3. IPC Drug Discovery Platform, Institut Paoli-Calmettes, 232 Boulevard de Sainte-Marguerite, 13009 Marseille, France

4. Laboratoire de Chemoinformatique, CNRS UMR7140, 1 rue Blaise Pascal, 67000 Strasbourg, France

Funder

Association pour la Recherche sur le Cancer

Agence Nationale de la Recherche

Institut National Du Cancer

Cancerop??le PACA

Fondation pour la Recherche Medicale

Aix-Marseille University