Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites-Reference-Cited by-同舟云学术

Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites

Published:2018-08-13 Issue:17 Volume:61 Page:7849-7860
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Paludetto Marie-Noëlle¹²³⁴,Bijani Christian¹,Puisset Florent²³⁴,Bernardes-Génisson Vania¹³,Arellano Cécile²³,Robert Anne¹^ORCID

Affiliation:

1. Laboratoire de Chimie de Coordination du CNRS (LCC−CNRS), Université de Toulouse, 205 route de Narbonne, BP 44099, 31077 Toulouse, Cedex 4, France

2. Centre de Recherches en Cancérologie de Toulouse (CRCT), INSERM UMR1037, Université de Toulouse, 2 avenue Hubert Curien, CS53717, 31037 Toulouse, Cedex 1, France

3. Université Paul Sabatier, 31400 Toulouse, France

4. Pharmacie, Institut Claudius Regaud, IUCT-O, 31037 Toulouse, Cedex 1, France

Funder

Institut National de la Sant? et de la Recherche M?dicale

Institut Claudius Regaud

Centre National de la Recherche Scientifique

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00812