Allosteric Modulator Discovery: From Serendipity to Structure-Based Design-Reference-Cited by-同舟云学术

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design

Published:2019-02-28 Issue:14 Volume:62 Page:6405-6421
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lu Shaoyong¹²,He Xinheng¹,Ni Duan¹,Zhang Jian¹²^ORCID

Affiliation:

1. Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Clinical and Fundamental Research Center, Renji Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China

2. Medicinal Bioinformatics Center, Shanghai Jiao-Tong University School of Medicine, Shanghai 200025, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Innovation Team Diagnosis and Treatment of Major Cardiovascular Diseases of High-Level Universities in Shanghai

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01749

Reference198 articles.

1. A Chemical Perspective on Allostery

2. The concept of allosteric modulation: an overview

3. Controlling Allosteric Networks in Proteins

4. Allosteric post-translational modification codes

5. Allostery in Disease and in Drug Discovery

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