Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously-Reference-Cited by-同舟云学术

Discovery of Novel Pazopanib-Based HDAC and VEGFR Dual Inhibitors Targeting Cancer Epigenetics and Angiogenesis Simultaneously

Published:2018-05-22 Issue:12 Volume:61 Page:5304-5322
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zang Jie¹,Liang Xuewu¹,Huang Yongxue²,Jia Yuping³,Li Xiaoyang⁴^ORCID,Xu Wenfang¹,Chou C. James⁴^ORCID,Zhang Yingjie¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmaceutical of Science, Shandong University, Ji’nan, Shandong 250012, P. R. China

2. Weifang Bochuang International Biological Medicinal Institute, Weifang, Shandong 261061, P. R. China

3. Shandong Academy of Pharmaceutical Sciences, Ji’nan, Shandong 250101, P. R. China

4. Department of Drug Discovery and Biomedical Sciences, South Carolina College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, United States

Funder

Ministry of Science and Technology of the People's Republic of China

Shandong Province

Shandong University

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00384

Reference42 articles.

1. Targeted cancer therapy

2. Hallmarks of Cancer: The Next Generation

3. The Hallmarks of Cancer

4. Polypharmacology: Challenges and Opportunities in Drug Discovery

5. Polypharmacology – Foe or Friend?

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