Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase-Reference-Cited by-同舟云学术

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Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase

Published:2018-06-05 Issue:12 Volume:61 Page:5199-5221
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Winterton Sarah E.,Capota Emanuela,Wang Xiaoyu,Chen Hong,Mallipeddi Prema L.,Williams Noelle S.,Posner Bruce A.,Nijhawan Deepak,Ready Joseph M.^ORCID

Funder

National Cancer Institute

Welch Foundation

Damon Runyon Cancer Research Foundation

Cancer Prevention and Research Institute of Texas

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00052

Reference34 articles.

1. Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

2. Triglyceride accumulation protects against fatty acid-induced lipotoxicity

3. Biochemical and physiological function of stearoyl-CoA desaturase

4. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

5. Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

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1. The fatty acid omega hydroxylase genes (CYP4 family) in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD): An RNA sequence database analysis and review;Biochemical Pharmacology;2024-05

2. Non-benzenoid N-aryl oxalamide: synthesis of troponyl-oxalamide peptides by Pd(ii)-catalyzed C(sp³)–H functionalization of glycinamides;Organic & Biomolecular Chemistry;2024

3. Deciphering the Role of Fatty Acid–Metabolizing CYP4F11 in Lung Cancer and Its Potential As a Drug Target;Drug Metabolism and Disposition;2023-11-16

4. Advances in regulation and function of stearoyl-CoA desaturase 1 in cancer, from bench to bed;Science China Life Sciences;2023-07-11

5. Selective Synthesis of Cyclic Nitroene‐Sulfonamides from Aliphatic Sulfamides and NOBF₄;European Journal of Organic Chemistry;2023-05-23

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