α-Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease

Author:

Moreno-Cinos Carlos1ORCID,Sassetti Elisa23,Salado Irene G.1,Witt Gesa2,Benramdane Siham1,Reinhardt Laura4,Cruz Cristina D.5,Joossens Jurgen1,Van der Veken Pieter1ORCID,Brötz-Oesterhelt Heike4,Tammela Päivi5ORCID,Winterhalter Mathias3,Gribbon Philip2,Windshügel Björn2ORCID,Augustyns Koen1ORCID

Affiliation:

1. Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium

2. Fraunhofer Institute for Molecular Biology and Applied Ecology, ScreeningPort, Schnackenburgallee 114, 22525 Hamburg, Germany

3. Department of Life Sciences and Chemistry, Jacobs University Bremen gGmbH, Campus Ring 1, 28759 Bremen, Germany

4. Interfaculty Institute for Microbiology and Infection Medicine, University of Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany

5. Drug Research Program, Division of Pharmaceutical Biosciences, University of Helsinki, Viikinkaari 5E, FI-00014 Helsinki, Finland

Funder

Academy of Finland Grants

DFG

MSCA-ITN-2014-ETN project INTEGRATE

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference67 articles.

1. Seven Ways to Preserve the Miracle of Antibiotics

2. Targeting Antibiotic Resistance

3. Resistance fighters

4. Antimicrobial Resistance: Global Report on Surveillance; World Health Organization, 2014.

5. Update on the antibiotic resistance crisis

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