Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity-Reference-Cited by-同舟云学术

Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity

Published:2018-06-25 Issue:14 Volume:61 Page:6140-6152
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bertamino Alessia¹,Iraci Nunzio¹^ORCID,Ostacolo Carmine²^ORCID,Ambrosino Paolo³,Musella Simona²,Di Sarno Veronica¹,Ciaglia Tania¹,Pepe Giacomo¹,Sala Marina¹^ORCID,Soldovieri Maria Virginia³,Mosca Ilaria³,Gonzalez-Rodriguez Sara⁴,Fernandez-Carvajal Asia⁴,Ferrer-Montiel Antonio⁴,Novellino Ettore²^ORCID,Taglialatela Maurizio⁵^ORCID,Campiglia Pietro¹,Gomez-Monterrey Isabel²^ORCID

Affiliation:

1. Department of Pharmacy, University of Salerno, Via G. Paolo II 132, 84084 Fisciano, Salerno Italy

2. Department of Pharmacy, University Federico II of Naples, Via D. Montesano 49, 80131 Naples, Italy

3. Department of Medicine and Health Science V. Tiberio, University of Molise, Via F. de Sanctis, 86100 Campobasso, Italy

4. Institute of Molecular and Cellular Biology, Universitas Miguel Hernández, Avda de la Universidad, 032020 Elche, Spain

5. Department of Neuroscience, Reproductive Sciences and Dentistry, University Federico II of Naples, Via Pansini, 5, 80131 Naples, Italy

Funder

Generalitat Valenciana

Ministerio de Economía y Competitividad

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00545

Reference88 articles.

1. Identification of a cold receptor reveals a general role for TRP channels in thermosensation

2. A TRP Channel that Senses Cold Stimuli and Menthol

3. ThermoTRP channels and beyond: mechanisms of temperature sensation

4. TRPM8, a Sensor for Mild Cooling in Mammalian Sensory Nerve Endings

5. Inhibition of TRPM8 by Icilin Distinct from Desensitization Induced by Menthol and Menthol Derivatives

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