Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase-Reference-Cited by-同舟云学术

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase

Published:2017-12-05 Issue:23 Volume:60 Page:9860-9873
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Butler Christopher R.¹^ORCID,Beck Elizabeth M.¹,Harris Anthony²,Huang Zhen¹,McAllister Laura A.¹,am Ende Christopher W.²^ORCID,Fennell Kimberly²,Foley Timothy L.²,Fonseca Kari¹,Hawrylik Steven J.²,Johnson Douglas S.¹,Knafels John D.²,Mente Scot¹,Noell G. Stephen²,Pandit Jayvardhan²,Phillips Tracy B.²,Piro Justin R.¹,Rogers Bruce N.²,Samad Tarek A.¹,Wang Jane³,Wan Shuangyi³,Brodney Michael A.¹

Affiliation:

1. Pfizer Worldwide Research and Development, 1 Portland Street, Cambridge, Massachusetts 02139, United States

2. Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, Connecticut 06340, United States

3. WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01531

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1. How neuroinflammation contributes to neurodegeneration