Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites-Reference-Cited by-同舟云学术

Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites

Published:2018-02-04 Issue:5 Volume:61 Page:1969-1989
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Selvam Chelliah¹,Lemasson Isabelle A.¹,Brabet Isabelle²,Oueslati Nadia²,Karaman Berin¹,Cabaye Alexandre¹,Tora Amélie S.²,Commare Bruno¹³,Courtiol Tiphanie¹,Cesarini Sara¹,McCort-Tranchepain Isabelle¹,Rigault Delphine¹,Mony Laetitia¹⁴,Bessiron Thomas⁵,McLean Heather⁵,Leroux Frédéric R.³^ORCID,Colobert Françoise³^ORCID,Daniel Hervé⁵,Goupil-Lamy Anne⁶,Bertrand Hugues-Olivier⁶,Goudet Cyril²,Pin Jean-Philippe²,Acher Francine C.¹^ORCID

Affiliation:

1. Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, Université Paris Descartes, Sorbonne Paris Cité, 45 rue des Saints-Pères, 75270 Paris Cedex 06, France

2. IGF, CNRS, INSERM, Université Montpellier, F-34094 Montpellier, France

3. UMR 7509/CNRS/ECPM, Université de Strasbourg, 25 Rue Becquerel, 67087 Strasbourg 02, France

4. Institut de Biologie, Ecole Normale Supérieure, CNRS UMR 8197, INSERM U1024, PSL University, 46 rue d’Ulm, 75005 Paris, France

5. Pharmacologie et Biochimie de la Synapse, Université Paris-Sud/CNRS/NeuroPSI−UMR 9197, F-91405 Orsay, France

6. BIOVIA, Dassault Systèmes, 10 rue Marcel Dassault, CS 40501, 78946 Vélizy-Villacoublay Cedex, France

Funder

Agence Nationale de la Recherche

Fondation pour la Recherche M?dicale

Fondation de France

Centre National de la Recherche Scientifique

Retina France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01438

Reference84 articles.

1. Metabotropic glutamate receptors as drug targets: what's new?

2. Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

3. Organization and functions of mGlu and GABAB receptor complexes

4. Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

5. Native metabotropic glutamate receptor 4 depresses synaptic transmission through an unusual Gα q transduction pathway

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