Influence of a Basic Side Chain on the Properties of Hypoxia-Selective Nitro Analogues of the Duocarmycins: Demonstration of Substantial Anticancer Activity in Combination with Irradiation or Chemotherapy
Author:
Affiliation:
1. Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
Funder
Cancer Society of New Zealand
Health Research Council of New Zealand
Foundation for Research, Science and Technology
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00563
Reference59 articles.
1. CC-1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies
2. Duocarmycins - Natures Prodrugs?
3. Phase II study of adozelesin in untreated metastatic breast cancer
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