Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative
Author:
Affiliation:
1. EicOsis Human Health Inc., Subsidiary of EicOsis LLC, 1930 Fifth Street, Suite A, Davis, California 95616, United States
2. Synthia LLC, P.O. Box 1238, Gualala, California 95445, United States
Funder
National Institute of Environmental Health Sciences
National Cancer Institute
National Institute of Neurological Disorders and Stroke
National Institute on Drug Abuse
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01886
Reference56 articles.
1. The 2014 Bernard B. Brodie Award Lecture—Epoxide Hydrolases: Drug Metabolism to Therapeutics for Chronic Pain
2. PRELIMINARY CHROMATOGRAPHIC STUDIES ON THE METABOLITES AND PHOTODECOMPOSITION PRODUCTS OF THE JUVENOID 1-(4′ -ETHILPHENOXY)-6,7-EPOXY-3,7-DIMETHYL-2-OCTENE
3. Mammalian Metabolism and Environmental Degradation of the Juvenoid 1-(4'-Ethylphenoxy)-3,7-dimethyl-6,7-epoxy-
4. Arachidonic acid cytochrome P450 epoxygenase pathway
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