Systematic Study of the Glutathione Reactivity of N-Phenylacrylamides: 2. Effects of Acrylamide Substitution-Reference-Cited by-同舟云学术

Systematic Study of the Glutathione Reactivity of N-Phenylacrylamides: 2. Effects of Acrylamide Substitution

Published:2020-09-23 Issue:20 Volume:63 Page:11602-11614
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Birkholz Adam¹^ORCID,Kopecky David J.¹,Volak Laurie P.¹,Bartberger Michael D.¹^ORCID,Chen Yuping¹,Tegley Christopher M.¹,Arvedson Tara¹,McCarter John D.¹,Fotsch Christopher¹,Cee Victor J.¹^ORCID

Affiliation:

1. AMGEN Research, One Amgen Center Drive, Thousand Oaks, California 91320, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00749

Reference28 articles.

1. Structure-based design of targeted covalent inhibitors

2. Covalent inhibitors design and discovery

3. Targeted Covalent Inhibitors for Drug Design

4. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

5. Drug discovery for a new generation of covalent drugs

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