Chiral Alkyl Groups at Position 3(1′) of Pyropheophorbide-a Specify Uptake and Retention by Tumor Cells and Are Essential for Effective Photodynamic Therapy-Reference-Cited by-同舟云学术

Chiral Alkyl Groups at Position 3(1′) of Pyropheophorbide-a Specify Uptake and Retention by Tumor Cells and Are Essential for Effective Photodynamic Therapy

Published:2021-04-06 Issue:8 Volume:64 Page:4787-4809
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cheruku Ravindra R.¹,Tracy Erin C.²,Tabaczynski Walter¹,Missert Joseph R.¹,Baumann Heinz²,Pandey Ravindra K.¹^ORCID

Affiliation:

1. PDT Center and Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263, United States

2. Department of Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263, United States

Funder

National Cancer Institute

Photolitec, LLC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02090

Reference22 articles.

1. Nature: A rich source for developing multifunctional agents. tumor-imaging and photodynamic therapy

2. The role of porphyrin chemistry in tumor imaging and photodynamic therapy

3. Temoporfin (Foscan®, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin)-A Second-generation Photosensitizer†,‡

4. The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

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