Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction-Reference-Cited by-同舟云学术

Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction

Published:2020-05-07 Issue:11 Volume:63 Page:6238-6247
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Yunyuan¹,Xu Yixiang²,Song Rongrong¹,Ni Shuaishuai³,Liu Jiaqi¹,Xu Yanhong¹,Ren Yanliang¹^ORCID,Rao Li¹,Wang Yingjie⁴^ORCID,Wei Lin¹,Feng Lingling¹^ORCID,Su Chen⁵,Peng Chao⁵,Li Jian²^ORCID,Wan Jian¹^ORCID

Affiliation:

1. Key Laboratory of Pesticide & Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China

2. Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

3. Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200237, China

4. Shenzhen Bay Laboratory, Shenzhen 518055, Guangdong, China

5. National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai 201210, China

Funder

State Administration of Foreign Experts Affairs

Ministry of Education of the People's Republic of China

Central China Normal University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject