Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530)-Reference-Cited by-同舟云学术

Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530)

Published:2020-09-03 Issue:19 Volume:63 Page:11034-11044
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Randolph John T.¹^ORCID,Voight Eric A.¹^ORCID,Greszler Stephen N.¹^ORCID,Uno Brice E.¹,Newton James N.¹,Gleason Kenneth M.¹,Stolarik DeAnne¹,Van Handel Cecilia¹,Bow Daniel A. J.¹,DeGoey David A.¹^ORCID

Affiliation:

1. Abbvie Incorporated, Global Pharmaceutical Research and Development, 1 North Waukegan Road, North Chicago, Illinois 60064, United States

Funder

AbbVie

Enanta Pharmaceuticals, Inc

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00956

Reference27 articles.

1. Glecaprevir/Pibrentasvir: First Global Approval

2. Glecaprevir plus pibrentasvir for chronic hepatitis C virus genotype 1, 2, 4, 5, or 6 infection in adults with compensated cirrhosis (EXPEDITION-1): a single-arm, open-label, multicentre phase 3 trial

3. High SVR12 with 8-week and 12-week glecaprevir/pibrentasvir therapy: An integrated analysis of HCV genotype 1–6 patients without cirrhosis

4. Glecaprevir/pibrentasvir for 8 weeks in treatment-naïve patients with chronic HCV genotypes 1–6 and compensated cirrhosis: The EXPEDITION-8 trial

5. Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C virus infection

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