Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa)-Reference-Cited by-同舟云学术

Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa)

Published:2021-03-25 Issue:7 Volume:64 Page:3897-3910
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schaffner Arnaud-Pierre¹^ORCID,Sansilvestri-Morel Patricia¹,Despaux Nicole¹,Ruano Elisabeth¹,Persigand Thierry¹,Rupin Alain¹,Mennecier Philippe¹,Vallez Marie-Odile¹,Raimbaud Eric¹,Desos Patrice¹,Gloanec Philippe¹

Affiliation:

1. Institut de Recherches Servier, 11 rue des Moulineaux, 92150 Suresnes, et 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02072

Reference27 articles.

1. Low Levels of Thrombin Activatable Fibrinolysis Inhibitor (TAFI) in Patients with Chronic Liver Disease

2. Thrombin-activatable fibrinolysis inhibitor and the risk for recurrent venous thromboembolism

3. A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) – Part II: Enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis

4. The hyperfibrinolytic state of mice with combined thrombin-activatable fibrinolysis inhibitor (TAFI) and plasminogen activator inhibitor-1 gene deficiency is critically dependent on TAFI deficiency

5. In vivo regulation of plasminogen function by plasma carboxypeptidase B

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