Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity-Reference-Cited by-同舟云学术

Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity

Published:2021-03-23 Issue:7 Volume:64 Page:3707-3719
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kitagawa Hiroki¹,Kikuchi Masaki²,Sato Shin²,Watanabe Hisami²,Umezawa Naoki¹^ORCID,Kato Maiko¹,Hisamatsu Yosuke¹,Umehara Takashi²^ORCID,Higuchi Tsunehiko¹^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan

2. Laboratory for Epigenetics Drug Discovery, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan

Funder

Japan Agency for Medical Research and Development

Terumo Foundation for Life Sciences and Arts

Japan Society for the Promotion of Science

Nagoya City University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01371

Reference72 articles.