Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region

Author:

Luo Qinhong123,Ma Yue2,Liang Huiting3,Feng Yuan2,Liu Na23,Lian Chenshan23,Zhu Lizhi12,Ye Yuxin3,Liu Zhihong3,Hou Zhanfeng2,Chen Sijin2,Wang Yaqi2,Dai Chuan13ORCID,Song Chunli3,Zhang Min3,He Zhipeng3,Xing Yun3,Zhong Wanjin2,Li Shuiming4,Wu Jianlong1,Lu Fei2,Yin Feng23,Li Zigang23ORCID

Affiliation:

1. Department of Pharmacy, Shenzhen Second People’s Hospital (Shenzhen Institute of Translational Medicine), Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518060, China

2. State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China

3. Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen 518118, China

4. Shenzhen Key Laboratory of Microbiology and Gene Engineering, Shenzhen University, Shenzhen 518060, China

Funder

National Key Research and Development Program of China

Shenzhen Science and Technology Innovation Program

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Shenzhen-Hong Kong Institute of Brain Science

Shenzhen High-tech Zone Development Special Plan Pingshan District Innovation Platform Construction Project

Shenzhen High-level Hospital Construction Fund

National Center for Biological Medicine Technology Innovation

Shenzhen Key Medical Discipline Construction Fund

Proteomic Platform of Pingshan translational medicine center, Shenzhen Bay Laboratory

High-tech Zone Development Special Project of Shenzhen

Beijing National Laboratory of Molecular Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3