Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens

Author:

Mardirossian Mario1,Sola Riccardo2,Beckert Bertrand3,Valencic Erica4,Collis Dominic W. P.5,Borišek Jure6,Armas Federica2,Di Stasi Adriana2,Buchmann Jan37,Syroegin Egor A.7,Polikanov Yury S.78,Magistrato Alessandra6,Hilpert Kai9ORCID,Wilson Daniel N.3ORCID,Scocchi Marco2ORCID

Affiliation:

1. Department of Medical Sciences, University of Trieste, 34125 Trieste, Italy

2. Department of Life Sciences, University of Trieste, 34127 Trieste, Italy

3. Institut für Biochemie und Molekularbiologie, University of Hamburg, 20146 Hamburg, Germany

4. Institute for Maternal and Child Health-IRCCS “Burlo Garofolo”, 30137 Trieste, Italy

5. TiKa Diagnostics Ltd., SW 17 0RE London, U.K.

6. CNR-IOM at SISSA, 34136 Trieste, Italy

7. Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, United States

8. Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, United States

9. Institute of Infection and Immunology, St. George’s, University of London, SW 17 0RE London, U.K.

Funder

University of Illinois

Deutsche Zentrum fu??r Luft- und Raumfahrt

Institute of Infection and Immunity

Area Science Park

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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