Identification of a New Heterocyclic Scaffold for Inhibitors of the Polo-Box Domain of Polo-like Kinase 1-Reference-Cited by-同舟云学术

Identification of a New Heterocyclic Scaffold for Inhibitors of the Polo-Box Domain of Polo-like Kinase 1

Published:2020-11-11 Issue:22 Volume:63 Page:14087-14117
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Alverez Celeste N.¹²,Park Jung-Eun¹,Toti Kiran S.³^ORCID,Xia Yangliu¹,Krausz Kristopher W.¹,Rai Ganesha²^ORCID,Bang Jeong K.⁴^ORCID,Gonzalez Frank J.¹,Jacobson Kenneth A.³^ORCID,Lee Kyung S.¹^ORCID

Affiliation:

1. Chemistry Section, Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States

2. Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States

3. Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States

4. Division of Magnetic Resonance, Korea Basic Science Institute, Cheongju 28119, Republic of Korea

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01669

Reference77 articles.

1. Polo-like kinases: structural variations lead to multiple functions