Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer-Reference-Cited by-同舟云学术

Degradation of Polo-like Kinase 1 by the Novel Poly-Arginine N-Degron Pathway PROTAC Regulates Tumor Growth in Nonsmall Cell Lung Cancer

Published:2023-12-17 Issue: Volume: Page:
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gunasekaran Pethaiah¹²,Hwang Yeon Sil¹²,Lee Gong-Hyeon²,Park Jaehui³,Kim Jung Gi⁴,La Yeo Kyung¹,Park Nam Yeong¹,Kothandaraman Rajesh²,Yim Min Su⁵,Choi Joonhyeok¹,Kim Hak Nam¹,Park Il Yeong³,Lee Soo Jae³,Kim Mi-Hyun⁶,Cha-Molstad Hyunjoo⁴,Shin Song Yub⁷^ORCID,Ryu Eun Kyoung¹⁸^ORCID,Bang Jeong Kyu¹²⁸^ORCID

Affiliation:

1. Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk 28119, Republic of Korea

2. Dandicure Inc, Ochang, Chungbuk 28119, Republic of Korea

3. College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk 28160, Republic of Korea

4. Nucleic Acid Therapeutics Research Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanji-ro, Ochang, Cheongwon, Chungbuk 28116, Republic of Korea

5. Division of Vaccine Development Coordination, Center for Vaccine Research, National Institute of Infectious Diseases, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju 28159, Republic of Korea

6. Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea

7. Department of Cellular and Molecular Medicine, School of Medicine, Chosun University, Gwangju 61452, Republic of Korea

8. Department of Bio-Analytical Science, University of Science & Technology, Daejeon 34113, Republic of Korea

Funder

Korea Drug Development Fund

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01493

Reference62 articles.