Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial-Reference-Cited by-同舟云学术

Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial

Published:2021-02-15 Issue:4 Volume:64 Page:1873-1888
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Koriyama Yuji,Hori Akihiro,Ito Hisanori,Yonezawa Shuji,Baba Yoshiyasu,Tanimoto Norihiko,Ueno Tatsuhiko,Yamamoto Shiho,Yamamoto Takahiko,Asada Naoya,Morimoto Kenji,Einaru Shunsuke,Sakai Katsunori,Kanazu Takushi,Matsuda Akihiro,Yamaguchi Yoshitaka,Oguma Takuya^ORCID,Timmers Maarten¹,Tritsmans Luc¹,Kusakabe Ken-ichi^ORCID,Kato Akira,Sakaguchi Gaku

Affiliation:

1. Janssen Research & Development, a division of Janssen Pharmaceutica N.V., Turnhoutseweg 30, B-2340 Beerse, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01917

Reference58 articles.

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