Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38α MAP Kinase Inhibitors-Reference-Cited by-同舟云学术

Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38α MAP Kinase Inhibitors

Published:2020-05-28 Issue:13 Volume:63 Page:7347-7354
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pedreira Júlia G. B.¹²^ORCID,Nahidino Philipp³,Kudolo Mark³,Pantsar Tatu³⁴^ORCID,Berger Benedict-Tilman⁵⁶^ORCID,Forster Michael³,Knapp Stefan⁵⁶^ORCID,Laufer Stefan³⁷⁸^ORCID,Barreiro Eliezer J.¹²^ORCID

Affiliation:

1. Laboratory of Evaluation and Synthesis of Bioactive Substances (LASSBio), Federal University of Rio de Janeiro (UFRJ), 21944-971 Rio de Janeiro, Brazil

2. Graduate Program of Chemistry (PGQu), Chemistry Institute, UFRJ, 21941-909 Rio de Janeiro, Brazil

3. Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität, Auf der Morgenstelle 8, 72076 Tübingen, Germany

4. School of Pharmacy, University of Eastern Finland, Yliopistonranta 1, 70210 Kuopio, Finland

5. Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany

6. Structural Genomics Consortium (SGC), Buchman Institute for Life Sciences, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 15, D-60438 Frankfurt am Main, Germany

7. Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, 72076 Tübingen, Germany

8. Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076 Tübingen, Germany

Funder

Deutscher Akademischer Austauschdienst

Orionin Tutkimuss??ti?

Deutschen Konsortium f?r Translationale Krebsforschung

Deutsche Forschungsgemeinschaft

H2020 Marie Sklodowska-Curie Actions

Wellcome Trust

Instituto Nacional de Ci?ncia e Tecnologia de F?rmacos e Medicamentos

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Eberhard Karls Universit?t T?bingen