A Sustainable and Catalytic Synthesis of Dibenzosuberone

Author:

Nori Valeria1ORCID,Della Penna Francesca1,Cocco Emanuele1ORCID,Mantegazza Simone2,Razzetti Gabriele2,Quattrocchi Giuseppe2,Pesciaioli Fabio1ORCID,Carlone Armando13ORCID

Affiliation:

1. Department of Physical and Chemical Sciences Università degli Studi dell'Aquila via Vetoio 67100 L'Aquila Italy

2. Laboratory of Research and Development Dipharma Francis S.r.l. via Bissone 5 20021 Baranzate Italy

3. INSTM Consorzio Nazionale per la Scienza e Tecnologia dei Materiali RU L'Aquila

Abstract

AbstractDibenzosuberone (DBS) is a key intermediate for the synthesis of relevant active pharmaceutical ingredients (APIs) for the treatment of several diseases related to the central nervous system. Herein, the design and development of a milder and greener approach to improve the well‐established methodology for the synthesis of DBS limiting waste production via the use of immobilized catalysts are presented.

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

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