Helicobacter pylori Xanthine–Guanine–Hypoxanthine Phosphoribosyltransferase—A Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Author:

Keough Dianne T.1,Wun Shun Jie1,Baszczyňski Ondřej2ORCID,Eng Wai Soon1,Špaček Petr2,Panjikar Santosh34,Naesens Lieve5ORCID,Pohl Radek2,Rejman Dominik2,Hocková Dana2,Ferrero Richard L.678,Guddat Luke W.1ORCID

Affiliation:

1. The School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Queensland, Australia

2. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague 6 CZ-166 10, Czech Republic

3. Australian Synchrotron, ANSTO, 800 Blackburn Road, Clayton 3168, Victoria, Australia

4. Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Australia

5. Katholieke Universiteit, Leuven, Rega Institute for Medical Research, Leuven 3000, Belgium

6. Hudson Institute of Medical Research, Clayton 3800, Victoria, Australia

7. Department of Molecular and Translational Sciences, Monash University, Clayton 3800, Australia

8. Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton 3800, Australia

Funder

National Health and Medical Research Council

Grantov? Agentura Cesk? Republiky

State Government of Victoria

National Foundation for Medical Research and Innovation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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