Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042)

Author:

Hahn Michael G.1ORCID,Lampe Thomas1,El Sheikh Sherif1,Griebenow Nils1,Woltering Elisabeth1,Schlemmer Karl-Heinz1,Dietz Lisa1,Gerisch Michael1,Wunder Frank1,Becker-Pelster Eva-Maria1,Mondritzki Thomas12,Tinel Hanna1,Knorr Andreas1,Kern Armin1,Lang Dieter1ORCID,Hueser Joerg1,Schomber Tibor1,Benardeau Agnes1,Eitner Frank13,Truebel Hubert12,Mittendorf Joachim1,Kumar Vijay4,van den Akker Focco4ORCID,Schaefer Martina5,Geiss Volker1,Sandner Peter16,Stasch Johannes-Peter17

Affiliation:

1. Research and Development, Bayer AG, Pharmaceuticals, Aprather Weg 18a, 42113 Wuppertal, Germany

2. University of Witten/Herdecke, 58455 Witten, Germany

3. Division of Nephrology and Clinical Immunology, RWTH Aachen University, 52074 Aachen, Germany

4. Department of Biochemistry, Case Western Reserve University, 44106 Cleveland, Ohio, United States

5. Lead Discovery−Structural Biology, Nuvisan ICB GmbH, 13353 Berlin, Germany

6. Institute of Pharmacology, Hannover Medical School, 30625 Hannover, Germany

7. Institute of Pharmacy, University Halle-Wittenberg, 06120 Halle, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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