Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors

Author:

Ye Jiqing1,Chu Adrian Jun2,Harper Rachel2,Chan Shu Ting1,Shek Tsun Lam3,Zhang Yufeng3,Ip Margaret2,Sambir Mariya4,Artsimovitch Irina4,Zuo Zhong3ORCID,Yang Xiao2,Ma Cong1ORCID

Affiliation:

1. State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, People’s Republic of China

2. Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China

3. School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, People’s Republic of China

4. Department of Microbiology and the Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, United States

Funder

Food and Health Bureau

Research Grants Council, University Grants Committee

Hong Kong Polytechnic University

U.S. Department of Health and Human Services

Chinese University of Hong Kong

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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