Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor-Reference-Cited by-同舟云学术

Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor

Published:2021-03-18 Issue:7 Volume:64 Page:3956-3975
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Hefeng¹²,Peng Xia³,Dai Yang³,Shao Jingwei¹²,Ji Yinchun³,Sun Yiming³,Liu Bo³,Cheng Xu³²,Ai Jing³²,Duan Wenhu¹²^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, P. R. China

2. University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, P. R. China

3. Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

Shanghai Municipal Health and Family Planning Commission

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02093

Reference54 articles.