Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators-Reference-Cited by-同舟云学术

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators

Published:2020-12-05 Issue:24 Volume:63 Page:15979-15996
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Shuai¹,Wang Sai-Qi²,Teng Qiu-Xu³,Yang Linlin⁴,Lei Zi-Ning³,Yuan Xiao-Han¹,Huo Jun-Feng¹,Chen Xiao-Bing²,Wang Mengru⁴,Yu Bin¹^ORCID,Chen Zhe-Sheng³^ORCID,Liu Hong-Min¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China

2. Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan Cancer Institute, Zhengzhou 450008, China

3. College of Pharmacy and Health Sciences, St. John’s University, Queens, New York 11439, United States

4. Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Program for Science & Technology Innovation Talents in Universities of Henan Province

1000 Talents Program of Central plains

Medical Science and Technique Foundation of Henan Province

Science and Technique Foundation of Henan Province

Publisher

American Chemical Society (ACS)

Subject