Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer-Reference-Cited by-同舟云学术

Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer

Published:2021-01-05 Issue:1 Volume:64 Page:741-767
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cheruku Ravindra R.¹,Cacaccio Joseph¹,Durrani Farukh A.¹,Tabaczynski Walter A.¹,Watson Ramona¹,Siters Kevin²,Missert Joseph R.¹,Tracy Erin C.³,Dukh Mykhaylo¹,Guru Khurshid⁴^ORCID,Koya Richard C.⁵,Kalinski Pawel⁵,Baumann Heinz³,Pandey Ravindra K.¹^ORCID

Affiliation:

1. PDT Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center Buffalo, Buffalo, New York 14223, United States

2. Photolitec, LLC, 73 High Street, Buffalo, New York 14223, United States

3. Molecular and Cellular Biology, Roswell Park Comprehensive Cancer Center Buffalo, Buffalo, New York 14263, United States

4. Department of Urology, Roswell Park Comprehensive Cancer Center Buffalo, Buffalo, New York 14263, United States

5. Department of Immunology, Roswell Park Comprehensive Cancer Center Buffalo, Buffalo, New York 14263, United States

Funder

National Cancer Institute

Roswell Park Alliance Foundation, Roswell Park Cancer Institute

Photolitec LLC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01735

Reference48 articles.

1. Photodynamic therapy of cancer. Basic principles and applications

2. Photodynamic Therapy: A Brief History

3. Tetrakis( p -Carboranylthio-Tetrafluorophenyl)Chlorin (TPFC): Application for Photodynamic Therapy and Boron Neutron Capture Therapy

4. The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

5. Current Developments in Using MESO-(TETRA) Substituted Porphyrins for PDT

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