Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity-Reference-Cited by-同舟云学术

Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity

Published:2021-02-02 Issue:3 Volume:64 Page:1701-1712
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Qingqing¹,Liu Zhikun¹,Hua Wuyang¹,Gou Shaohua¹²^ORCID

Affiliation:

1. Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China

2. Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu Province 211189, China

Funder

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02048

Reference47 articles.

1. Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

2. Theta, a new class of glutathione transferases purified from rat and man

3. Characterization of rat spleen prostaglandin H d-isomerase as a sigma-class GSH transferase

4. Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

5. Zeta, a novel class of glutathione transferases in a range of species from plants to humans

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