Stimuli-responsive biotin-anchored prodrug for the targeted delivery of anti-cancer agent NBDHEX with turn-on NIR fluorescence-Reference-Cited by-同舟云学术

Stimuli-responsive biotin-anchored prodrug for the targeted delivery of anti-cancer agent NBDHEX with turn-on NIR fluorescence

Published:2024 Issue:25 Volume:60 Page:3397-3400
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Kesarwani Rahul¹^ORCID,Pal Nikita¹^ORCID,Bhabak Krishna P.¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

Abstract

Biothiol-responsive turn-on fluorogenic prodrug RK-296 was developed for the sustained delivery of the anti-cancer agent and GSTP1 inhibitor NBDHEX with turn-on NIR fluorescence.

Funder

Indian Council of Medical Research

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC00210E

Reference25 articles.

1. Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

2. Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death

3. Glutathione S-Transferases in Cancer

4. Role of glutathioneS-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance

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